The oxidation of ketone bodies by rat brain mitochondria
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چکیده
منابع مشابه
Effect of hyperphenylalaninaemia on lipid synthesis from ketone bodies by rat brain.
The effect of hyperphenylalaninaemia on the metabolism of ketone bodies in vivo and in vitro by developing rat brain was investigated. The incorporation in vivo of [14C]acetoacetate into cerebral lipids was decreased by both chronic (for 3 days) and acute (for 6h) hyperphenylalaninaemia induced by injecting phenylalanine into 1-week-old rats. In studies in vitro it was observed that the incorpo...
متن کاملThe effect of hexokinase and tricarboxylic acid-cycle intermediates on fatty acid oxidation and formation of ketone bodies by rat-liver mitochondria.
1. The oxidation of butyrate, hexanoate and octanoate by rat-liver mitochondria suspended in a tris-potassium chloride medium in the presence of malate and serum albumin has been investigated. 2. The oxidation of butyrate to acetoacetate was markedly decreased by the addition of a system competitive for ATP (hexokinase-glucose). 3. Serum albumin or tricarboxylic acid-cycle intermediates prevent...
متن کاملThe simultaneous oxidation of substrates by rat liver mitochondria [proceedings].
present study is consistent with there being no difference in glycaemia in the animals, suggesting that abnormalities of carbohydrate metabolism had not developed at this age. It has been shown that calorie supplementation of the diet during suckling can lead to a persistent increase in body lipid content, at least up to 60 days (Wurtman & Miller, 19766). The effect of excess calorie intake on ...
متن کاملUtilization of ketone bodies by mammalian tissues.
It is now well established that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are metabolized by many mammalian tissues and that the rate of utilization is mainly dependent on their availability in the circulation. The aim in this contribution is to summarize briefly the pathways of ketone-body metabolism and to discuss the role of ketone bodies m various tissues. For a detailed review o...
متن کاملThe determination of ketone bodies.
Roche, J., Michel, R. & Jouan, P. (1957). Ciba Foundation Colloq. Endocrin. 10, 168. Rosenberg, I. N. (1951). J. clin. Inve8t. 30, 1. Schultz, A. L., Sandhaus, S., Demorest, H. L. & Zieve, L. (1954). J. clin. Endrocrin. 14, 1062. Sprott, W. E. & Maclagan, N. F. (1955). Biochem. J. 59,288. Taurog, A., Briggs, F. N. & Chaikoff, I. L. (1952). J. biol. Chem. 194, 655. Taurog, A., Chaikoff, I. L. & ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1970
ISSN: 0014-5793
DOI: 10.1016/0014-5793(70)80050-3